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Renfrewshire, Scotland. The Semple family controlled part of this shire to the west of Glasgow. They were situated around the area of Castle Semple Loch, Lochwinnoch, Howwood, and along the Black Cart River. These lands, once owned by the Baloil clan, once Kings of Scotland, were given to the Sempill family for their support of Robert the Bruce during the Wars of Independence. The castle of Elistoun, part of which still stands, was the main house for generations, until Castle Semple was built by the Loch. A Peel still stands near there along with a Collegiate Church. Castle Semple was sold in the 1700s and was soon demolished in order for the new owner to build a very large mansion house. Many Semples still reside in the area.
The Semple family were lowlanders, many of whom left for Ireland to the Plantations and eventually, made it to the states. A few others left for the states directly from Scotland. Once here, most migrated to the frontiers and set up large families of Semple, Sample, and Samples.