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Basically whatever works for you, go for it. On the families that I have a lot of information, and I too have some going back to the 1700's. I make a notebook for say my grandfather and his children, one for great grandfather & his children and so forth. For the older lines, I don't have a lot of information, so I can combine 2 or 3 generations in the same notebook. To make them easy to find, I use the clear sleeves for say my gr gr father with his name on a clear colored tab, you can buy these stick on tabs separately. This makes his name extend farther to the outside, readily visible, for his children, I use the plastic tab dividers and insert the chldren's names making one for each child. If I have a photo of the individual, I put it in the clear sleeve that has their name on it then next, I add the Family Group Sheet. On one family, I even made my own white tabs for one generation, having them extended at a difference than the others. This has really helped me get more familiar with the individual families. It also helps me when I have 3 or 4 James or George to get that person in the correct family.