I have a Jesse McGuire (1787-1850) son of Rev Cornelius McGuire (abt. 1768-1811)and Ester Stratton of Floyd KY. Jesse married Elizabeth Garrett and had a son Emilech Garret McGuire who ended up in Cass MO in 1900.
Rev. Cornelius served with GR Clark, and his brother William (my 4G grandfather) is a RW pensioner. These men were living in both Tazewell VA (Clinch river) and Floyd KY (Big Sandy) in the early 19th century.
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