I am also researching these two individuals. I believe Daniel Conkle from PA who m. Elizabeth Marcus are Margaret's parents. I have nothing on Isaac yet. Did find his grave site. Located in Morgan Twsp., Gallia Co., OH. He was born 1822 and died February 8, 1886. Two other tombstones beside his with same date of death (Isaac and Dayton Moses Barrett). Probably his sons. All died suddenly.
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